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Younger Males Should Wait Longer Between COVID-19 Vaccines Over Myocarditis Risk, CDC Advises

by | Feb 28, 2022 | Wellness Blog: Covid

COVID-19 Virus

Update on COVID-19 Vaccines

February 28, 2022 — The Centers for Disease Control and Prevention (CDC) updated its vaccine recommendations on February 22 to say younger males age 12 to 39 should consider waiting longer between doses of the Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines to reduce the risk of myocarditis — an inflammation of the heart muscle.

“While absolute risk remains small”, some studies show “the relative risk for myocarditis is higher for males ages 12-39 years, and this risk might be reduced by extending the interval between the first and second dose,” the agency said. The CDC cited studies further showed in adolescents and adults alike, peak antibody responses and mRNA vaccine effectiveness may be increased with an interval longer than four weeks between the first and second doses.

Howbeit, the shorter interval (three weeks for Pfizer-BioNTech and four weeks for Moderna) between the first and second doses of the mRNA vaccines remains the recommended interval for adults 65 years and older, people who are immunocompromised, and others at high risk for severe COVID-19 disease.

The updated guidance most notably affects younger not fully vaccinated males, those who have received one or fewer jabs. The CDC estimates by age group the following percentages of American males not fully vaccinated: 12 to 17yrs (45%), 18-24yrs (42%), 25-39yrs (37.6%).

Omicron Name Used for Several Lineages of Coronavirus. 4U Health. Updated February 25, 2022.

N95 Masks Offer Better Protection Against COVID Omicron Variant Than Cloth Face Coverings, CDC Says. 4U Health. Updated February 24, 2022.

Saliva COVID Test Better Than Nasal Swabs To Detect Omicron, Study Says. 4U Health. Updated February 24, 2022.

About 4U Health

4U Health offers at-home lab testing to help you feel like your best self. Visit us at to learn about our COVID-19 Antibody Self-Collection At Home Test Kit, explore healthy living and wellness topics, and view our full at-home lab testing menu.

If you’re interested in hospital grade home PCR COVID test kits to detect COVID-19 (including Omicron and its other variants), check out 4U Health’s COVID-19 Active Infection Self-Collection Test. It’s approved for children 5+ and adults alike. For the timeliest results, we recommend having our “just-in-case” saliva kit stocked in your medicine cabinet so you can test on your terms. Overnight shipping is included and official digital results are typically within 24 hours of receipt by the lab.

Updated: February 28, 2022