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At-Home PGX Testing Options

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Personalize your prescriptions to your genetics to identify medications that work best for you from the comfort of your own home with no doctor’s order required!

4U Health’s At-Home PGX Tests, also known as pharmacogenetic testing, analyze certain genes in your body known to impact the usefulness of up to 224 medications in the following categories: anti-cancer, cardiovascular, diabetes, gastrointestinal, infectious disease, pain management, psychiatry (ADHD/anxiety/bipolar disorder/depression/schizophrenia), rheumatology, transplantation, and urology.

How It Works

Order Your 4U Health Self Collection At Home Lab Test Kit

Order Your Test

Order online with express delivery. In 1 to 2 days your DNA collection kit will arrive in plain packaging, ensuring a confidential testing experience.

4U Health At Home Lab Test DNA Swab Sample Icon

Collect Your Sample

Your kit contains everything you need to test from home. Simply collect your cheek swab sample using the at-home testing kit and instructions. Then return free of charge to the lab with the provided prepaid shipping label.

4U Health Receive Your At Home Lab Test Digital Results

Fast, Accurate Results

Typically you will receive electronic results within 2-5 days after receipt by the lab. Have complete trust in your lab report’s accuracy, as all 4U Health testing kits provide hospital-grade certified results.

Get Physician Support For Your 4U Health Self Collection At Home Lab Test

Get Physician Support

We’ve got you covered! A licensed physician orders your test and reviews your results. Your test includes free telehealth result explanation to help you maximize our laboratory services.

What will my test results show me?

Your pharmacogenetics (PGx) test results help you identify what meds work best for you. Eliminate trial and error prescribing. PGx testing gives you and your physicians genetic insight into your body’s ability to process different drugs. This test provides empirical results to help you and your provider select the best medicine from the beginning to achieve the best medical outcome.

  • Increased Drug Toxicity

Your body metabolizes the drug too rapidly, leading to potential adverse side effects of a standard dose.

  • Reduced Drug Efficacy

Your body metabolizes the drug too slowly, leading to the medication not working as intended.

  • Hypersensitivity Drug Risk

Your body’s genetic profile causes you to react severely to a typical drug dose.

Why Check Your Drug to Gene Interactions?

91% of people carry at least one drug-reactive gene variant1

64% of people have taken or will take at least one PGx relevant drug2

7% of hospital patients will experience an adverse drug reaction3

4U Health Medication Response (PGx Gene Test)

You want to match with the right medications based on your unique genetic profile

A medication response test can help reduce trial-and-error prescribing with personalized drugs and doses. Over 90% of the population has at least one actionable gene variant that may affect the usefulness of prescribed medications and cause side effects.1

Test to:

  • Discover which drugs may work more or less effectively for you
  • Learn which drugs may give you more or fewer side effects
  • Know in advance of being prescribed a medication if it’s likely the best option for you

Analyzes up to 20 of your genes that may affect the usefulness of up to 224 prescribed medications

The 4U Health Medication Response Tests may help you avoid taking medications that are not ideally suited to your genetic profile. We’ll analyze up to 20 of your genes and provide information about which drugs across up to 10 medical specialties may require dose adjustments, be less likely to work, or have an increased risk of side effects.

Depending on the option you choose, your report can classify up to 224 anti-cancer, cardiovascular, diabetes, gastrointestinal, infectious disease, pain management, psychiatry (ADHD/anxiety/bipolar disorder/depression/schizophrenia), rheumatology, transplantation, and urology drugs into three categories:

  • STANDARD PRECAUTIONS – Use as directed
  • USE WITH CAUTION – Moderate gene-drug interaction
  • CONSIDER ALTERNATIVES – Significant gene-drug interaction

This test might be right for you if:

  • You want a report you can share now or in the future with any pharmacist or physician to help increase the likelihood you are prescribed the best medication option
  • You are experiencing less than optimal results from currently prescribed medications
  • You are taking multiple prescription medications for multiple chronic conditions
  • You have a personal or family history of adverse drug reactions

Easily collect a DNA cheek swab from the comfort and privacy of your own home

Your DNA test kit includes everything required for your mouth swab sample. We provide detailed instructions and a prepaid shipping label to return your sample to the lab.

Parents, we’ve got you covered – test any child 2 years and older. Mouth swabs are easy and painless!

Our tests bring hospital-grade results to your home

Once we receive your test, we’ll send your physician-reviewed results usually within 2-5 days.  4U Health at-home test reports are both accurate and easy to read. Your test includes a free telehealth result explanation. Feel free to use your results to identify any potential gene to drug interactions for current or proposed prescriptions. Prior to stopping any medications, share your results with your doctor or pharmacist to guide a discussion if a change in your treatment plan is appropriate.

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Frequently Asked Questions

What will my test results show me?

Your pharmacogenetics (PGx) test results help you identify what meds work best for you. Eliminate trial and error prescribing. PGx testing gives you and your physicians genetic insight into your body’s ability to process different drugs. This test provides empirical results to help you and your provider select the best medicine from the beginning to achieve the best medical outcome.

For medicines you are currently or considering taking, screen for:

  • Increased Drug Toxicity

Your body metabolizes the drug too rapidly, leading to potential adverse side effects of a standard dose.

  • Reduced Drug Efficacy

Your body metabolizes the drug too slowly, leading to the medication not working as intended.

  • Hypersensitivity Drug Risk

Your body’s genetic profile causes you to react severely to a typical drug dose.

We also analyze your genetic predisposition to having an increased risk for the following four psychiatric diseases:

  • Psychiatric Genetic Disease Risk Assessment
  • Antipsychotic-Induced Tardive Dyskinesia: Medication-induced uncontrolled spontaneous movements.
  • Antipsychotic-Induced Hyperprolactinemia: Elevated prolactin levels that can interfere with the functioning of reproductive, endocrine, and metabolic systems.
  • Antipsychotic-Induced Weight Gain: Increased risk for weight gain when treated with antipsychotics.
  • Hyperhomocysteinemia-Depression: Elevated homocysteine is a highly sensitive marker for low folate status (common in patients diagnosed with depression).

Your result includes a free telehealth report explanation to help you get the most out of your test.

Psychiatric Medication Response (PGx Gene Test) – Sample Report

What's a medication response pharmacogenomics (PGx) gene test?

Our psychiatric pharmacogenomics (PGx) test provides essential information on 9 genes which may affect metabolism and response to 125+ drugs often used in the treatment of mental health disorders. Clinicians can use the personalized information provided with this PGx test to help select the best medication and dose for an individual patient, limiting potential adverse drug reactions.

Drug Metabolism Genotyping
Also known as pharmacokinetics, this analysis predicts the body’s impact on a drug. Its purpose is to determine patient-specific genetic variants that may influence the function of drug-metabolizing enzymes. It shows whether a patient is an ultrarapid metabolizer, extensive metabolizer, intermediate metabolizer, or poor metabolizer of a medication. Understanding your metabolizer phenotype is important, as it indicates how much of a drug may be active in the body to produce either therapeutic or toxic effects.

Drug Response Genotyping
Also known as pharmacodynamics, this analysis describes a drug’s predictive impact on the body. It considers the likelihood of a drug producing the desired therapeutic effect by identifying patient-specific genetic variants involved in how medications work. This can indicate the likelihood of a good (therapeutic) or bad (adverse) drug response.

What’s included in the at-home Medication Response (PGx Gene Test)?

You’ll receive everything you need in order to self-collect your test specimen!

  • Pre-paid shipping both ways
  • Easy to follow instructions
  • An at-home DNA collection kit (via an easy cheek swab)
  • Return protective envelope to mail sample to the lab for testing
  • Electronic passcode protected results available from your phone or computer
  • Free telehealth result explanation
  • Printable report to share with your doctor
  • Help along the way if you need it

What drugs does the Comprehensive Medication Response Test cover?

4U Health’s Comprehensive Medication Response Test informs you on the usefulness of 224 medications in the following categories: anti-cancer, cardiovascular, diabetes, gastrointestinal, infectious disease, pain management, psychiatry, rheumatology, transplantation, and urology.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

What drugs does the Psychiatric Medication Response Test cover?

4U Health’s Psychiatric Medication Response Test informs you on the usefulness of 125+ medications mainly used in mental health treatment, including but not limited to: Antiaddictives, Anti-ADHD Agents, Anticonvulsants, Antidepressants, Antipsychotics, Benzodiazepines, and other Neurological Agents.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

What drugs does the Cardiac Medication Response Test cover?

4U Health’s Cardiac Medication Response Test informs you on the usefulness of 40+ medications mainly used to help improve cardiovascular health, including Angiotensin II Receptor Antagonists, Antianginal Agents, Antiarrhythmics, Anticoagulants, Antiplatelets, Beta Blockers, Diuretics, and Statins.

Discover how your body is likely to metabolize this extensive list of cardiac drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

What drugs does the Pain Medication Response Test cover?

4U Health’s Pain Medication Response Test informs you on the usefulness of 40 medications in the following categories: Fibromyalgia Agents, Muscle Relaxants, NSAIDs, Opioids, Anti-Hyperuricemics, Anti-gout Agents, and Immunomodulators.

Discover how your body is likely to metabolize this extensive list of drugs and use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.

What's a drug-induced disease?

Clinicians prescribe medications to treat disease or alleviate symptoms. The last thing you might expect is that a prescribed medication may do more harm than good. An adverse drug reaction (ADR) refers to the unintended side effects of a prescribed medication. A drug-induced disease occurs when an ADR warrants a patient consulting a doctor or getting hospitalized.

ADRs and drug-induced diseases are a reality. FDA studies estimate that 7% of hospitalized patients have a severe adverse drug reaction.2 Drugs are approved by the FDA for use only if their potential benefits far outweigh the risks involved. But it’s important to note not all people react similarly to a drug. A particular medicine may benefit some people while causing others potentially life-threatening unintended side effects.

A drug response test like this alerts patients and guides clinicians through the practice of personalized medicine. It allows prescribers to empirically select the best medications based on a patient’s unique genetic traits. This test may increase the likelihood of an optimal therapeutic outcome and limit the chances of an adverse drug reaction.

What's personalized pharmacy therapy?

One of the transformative trends in medicine is personalized pharmacy therapy. With the advent of medication response PGx tests, physicians and pharmacists alike can individualize a patient’s drug therapy consistent with that patient’s unique genetic makeup.

Our Psychiatric Medication Response (PGx Gene Test) provides personalized medication guidance on 125+ medications mainly used in mental health treatment, including but not limited to: Antiaddictives, Anti-ADHD Agents, Anticonvulsants, Antidepressants, Antipsychotics, Benzodiazepines, and other Neurological Agents.

Does this test include result explanation?

This state-of-the-art genetic test includes at no additional charge result explanation by a healthcare professional to help you better understand your medication response report. We’ll give you the information necessary to have an informed discussion with your physicians and pharmacists to get the most out of your results.

What genes does the Comprehensive Medication Response Test analyze?

This is our most complete medication response test and analyzes 20 genes to identify 244 medications for potential genetic induced adverse drug reactions.

Analyzes 20 Genes:
ANKK1, DRD2, Apolipoprotein E, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, F2, F5, ITGB3, LPA, MTHFR, OPRM, SLCO1B1, TPMT, and VKORC1.

See Full List of Genes and Alleles Tested

What genes does the Psychiatric Medication Response Test analyze?

This test provides an analysis of 9 genes to identify 125+ medications often used in mental health treatment for potential genetic induced adverse drug reactions.

Analyzes 9 Genes:
ANKK1, DRD2, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2D6, MTHFR, OPRM1.

See Full List of Genes and Alleles Tested

What genes does the Cardiac Medication Response Test analyze?

This test provides an analysis of 13 genes to identify 40+ medications often used to help improve cardiovascular health for potential genetic induced adverse drug reactions.

Analyzes 13 Genes:
Apolipoprotein E, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, Factor II, Factor V Leiden, ITGB3, LPA, MTHFR, SLCO1B1, and VKORC1.

See Full List of Genes and Alleles Tested

What genes does the Pain Medication Response Test analyze?

This test provides an analysis of 8 genes to identify 40 medications often used in pain management for potential genetic induced adverse drug reactions.

Analyzes 8 Genes:
COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, OPRM, and TPMT.

See Full List of Genes and Alleles Tested

What factors commonly influence the body's response to a medication?

Multiple factors influence how a person reacts to a drug including:

  • Genetics
  • Age
  • Allergies
  • Medical History
  • Weight and Body Size

Who should not take this test?

The Psychiatric Medication Response (PGx Gene Test) is not suitable for the following groups of people:

  • Children under 2-years-old
  • Specimens collected in New York State

If you’re experiencing a severe adverse drug reaction, such as difficulty breathing, vision problems, hives, fever, or vomiting, we recommend you speak with your healthcare provider right away.

Can I buy now and use this test later?

Test now or within one year of purchase. This kit has a guaranteed expiration date of at least 12 months. That’s great news if you are buying now but want to test yourself in the future or gifting to a friend or family member for later use.

Where is my lab test performed?

4U Health tests meet national standards and are as accurate as services provided in a doctor’s office or hospital. We only work with the highest quality CLIA certified laboratories and health experts. All testing complies with state and federal regulations. And our clinicians provide medical oversight throughout the entire process.

Can I gift this test to a friend or family member?

All 4U Health tests are eligible for gifting. In fact, they make great presents. The recipient who receives your gift will simply open the kit, register it, and follow the collection instructions. Within a few days of sending to the lab, your friend or family member will receive secure electronic HIPAA compliant results all thanks to your generosity.

Will my Medication Response Test be covered by insurance?

Many physicians don’t routinely order a medication response PGx Gene test. That’s because DNA tests like this often require pre-authorization from insurance carriers. If denied, patients with insurance coverage may face unexpected medical bills often in excess of a thousand dollars.

With 4U Health you pay a fair price upfront and receive no surprise medical bills. 4U Health is not enrolled in Medicare or any other private insurance network. This test is not eligible for Medicare or any other federal or state-funded insurance program reimbursement.

Still have questions about the test?

So you still have unanswered questions. No worries, we’d love to hear from you. Reach us by e-mail, phone or chat and we will do our best to provide answers so you can determine if this is the best test for you or your child.

How is my privacy protected?

Rest assured; HIPAA security standards protect your data every step of the way while determining your gene to drug responses. Keeping your confidential data secure is our number one priority. We only share your information when required to deliver our products and services or where we are legally obligated to do so. Your results are securely protected and available for review in your online portal; always secure but easily accessible only to you.

Easy at Home

Easy at home

Test on your terms at a time and place that’s convenient for you!

Certified Lab Results

Certified Lab Results

Accuracy matters! Certified laboratories perform our hospital-grade at-home health testing to ensure the highest quality results.

Fast Results

Fast Results

Take control of your health with FAST results. You’ll typically receive your lab results in 2-5 days.

Simple-To-Understand Results

Simple-To-Understand Results

Your easy-to-read doctor-reviewed results are delivered securely to your inbox. But the best part is – our support team is always available to help you better understand your results.

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