$299.00
4U Health At-Home Cardiac Medication Response (PGx Gene Test)
DNA test to personalize your blood pressure, cholesterol and heart medicines to your genetics
4U Health’s Cardiac Medication Response Test analyzes 13 specific genes in your body known to impact the usefulness of 15 of the most common cardiovascular medications.
Finding the right medicines to treat heart and vascular problems can be a frustrating trial-and-error process that often includes unintended side effects. Get a personalized cardiac medicine report unique to your specific DNA to predict how you will respond to this extensive list of blood pressure medicines (Carvedilol, Metoprolol, Nebivolol, Propranolol, and More) cholesterol medicines (Atorvastatin, Pravastatin, Rosuvastatin, Simvastatin, and more) Plavix, and Warfarin. Share your results with your prescribing physician(s) to help optimize current medications, as well as the future selection of drugs most likely to provide optimal heart health and to limit risk of adverse side effects.
- Check your body's response to 15 commonly prescribed cardiac drugs
- Simple at-home DNA cheek swab
- Recommended for ages 2 years and older
- Upgrade to test 120+ medicines
$299.00
4U Health Cardiac Medication Response (PGx Gene Test)
Analyzes 13 of your genes that may affect the usefulness of 15 common cardiovascular medicines
We’ll analyze 13 of your genes for important genetic variations in your DNA that may affect your response to medicines used to treat abnormal heartbeats (atrial fibrillation & other arrhythmias), atherosclerosis (plaque in the arteries), blood clots, chest pain, heart attack, high blood pressure, high cholesterol, heart failure, and stroke.
Results show which drugs may require dose adjustments, be less likely to work, or have an increased risk of side effects. Your report classifies 15 commonly prescribed cardiac drugs into three categories:
- STANDARD PRECAUTIONS – No known interaction
- USE WITH CAUTION – Moderate gene-drug interaction
- CONSIDER ALTERNATIVES – Serious gene-drug interaction
You want to match with the right cardiovascular medicines based on your unique DNA
A medication response test can help reduce trial-and-error prescribing with personalized drugs and doses. Over 90% of the population has at least one actionable gene variant that may affect the usefulness of prescribed medications and cause side effects.1
Test to:
- Find which heart drugs may work more or less effectively for you
- Learn which heart drugs may give you more or fewer side effects
- Know in advance of being prescribed a heart medication if it’s likely the best option for you
This test might be right for you if:
- You want a report you can share now or in the future with any pharmacist or physician to help increase the likelihood you are prescribed the best cardiac medication option
- You are experiencing less than optimal results from currently prescribed heart medications
- You plan to take a new cardiovascular prescription
- You have a personal or family history of adverse drug reactions
Easily collect a cheek swab from the comfort and privacy of your own home
Your DNA test kit includes everything required for your mouth swab sample. We provide detailed instructions and a prepaid shipping label to return your sample to the lab.
Parents, we’ve got you covered – although we recommend for children 2 years and older, you may test infants as well. Mouth swabs are easy and painless!
Our tests bring hospital-grade results to your home
Once we receive your test, we’ll send your physician-reviewed results usually within 2-7 business days. 4U Health at-home test reports are both accurate and easy to read. Use your results to identify any potential gene to drug interactions for current or proposed prescriptions. Prior to stopping any medications, share your results with your doctor or pharmacist to guide a discussion if a change in your treatment plan is appropriate.
This Test
This Test
Cardiac Medication Response
(PGx Gene Test)
Our Cardiac Medication Response Test analyzes 13 specific genes in your body known to impact the usefulness of 15 common cholesterol, blood pressure and other heart focused medicines. It’s an ideal test to check your body’s response to many leading cardiac medications to help select the proper drug and dose from the onset of your treatment.
- Assess the body’s response to 15 commonly prescribed cardiac drugs
Cardiac Medication Response (PGx Gene Test)
Our Cardiac Medication Response Test analyzes 13 specific genes in your body known to impact the usefulness of 15 common cholesterol, blood pressure and other heart focused medicines. It’s an ideal test to check your body’s response to many leading cardiac medications to help select the proper drug and dose from the onset of your treatment.
- Assess the body’s response to 15 commonly prescribed cardiac drugs
$299.00
$299.00
Upgrade Test Option
Upgrade Test Option
Comprehensive Medication Response
(PGx Gene Test)
4U Health’s Comprehensive Medication Response Test analyzes 20 specific genes in your body known to impact the usefulness of 120+ medications. Checks your body’s response to heart medicines + anti-cancer, autoimmune, cardiovascular, gastrointestinal, infectious disease, mental health, neurology, pain management, rheumatology, urology, and more.
- Assesses your body’s response to 120+ prescribed drugs
Comprehensive Medication Response (PGx Gene Test)
4U Health’s Comprehensive Medication Response Test analyzes 20 specific genes in your body known to impact the usefulness of 120+ medications. Checks your body’s response to heart medicines + anti-cancer, autoimmune, cardiovascular, gastrointestinal, infectious disease, mental health, neurology, pain management, rheumatology, urology, and more.
- Assesses your body’s response to 120+ prescribed drugs
$389.00
$389.00
Digital Results
Usually within 2 to 7 business days of your sample arriving at the lab, receive secure electronic results on your device of choice
Simple
Simple to understand results to identify potential harmful drug to gene interactions.
Individualized
Your individualized genetic report ranks 15 common cardiac medications to help guide current and future selection of drugs that increase the likelihood of the best medical outcome.
Useful Results
Share your hospital-grade results with your doctors and pharmacist to eliminate trial and error prescribing – ensure the best selection of cardiovascular medicines to efficiently treat your symptoms while reducing risks of negative side effects.
How It Works
Order Your Test
Order online with express delivery. In 1 to 2 days your DNA collection kit will arrive in plain packaging, ensuring a confidential testing experience.
Collect Your Sample
Your kit contains everything you need to test from home. Simply collect your cheek swab sample using the at-home testing kit and instructions. Then return free of charge to the lab with the provided prepaid shipping label.
Fast, Accurate Results
Typically you will receive electronic results within 2-7 business after receipt by the lab. Have complete trust in your lab report’s accuracy, as all 4U Health testing kits provide hospital-grade certified results.
Get Physician Support
We’ve got you covered! A licensed physician orders your test and reviews your results. Share your report with your prescribing medical providers to maximize our laboratory services.
Frequently Asked Questions
What’s included in the at-home Medication Response (PGx Gene Test)?
You’ll receive everything you need in order to self-collect your test specimen!
- Pre-paid shipping both ways
- Easy to follow instructions
- An at-home DNA collection kit (via an easy cheek swab)
- Return protective envelope to mail sample to the lab for testing
- Electronic passcode protected results available from your phone or computer
- Printable report to share with your doctor
- Physician oversight throughout the entire testing process
- Help along the way if you need it
What will my pharmacogenetics test result show me?
Your pharmacogenetics (PGx) test results help you identify what meds work best for you. Eliminate trial and error prescribing. PGx testing gives you and your physicians genetic insight into your body’s ability to process different drugs. This test provides empirical results to help you and your provider select the best medicine from the beginning to achieve the best heart health outcome.
For medicines you are currently or considering taking, screen for:
- Increased Drug Toxicity
Your body metabolizes the drug too rapidly, leading to potential adverse side effects of a standard dose.
- Reduced Drug Efficacy
Your body metabolizes the drug too slowly, leading to the medication not working as intended.
- Hypersensitivity Drug Risk
Your body’s genetic profile causes you to react severely to a typical drug dose.
Share your results with your prescribing physician(s) to avoid dangerous drug to gene interactions. View a Cardiac Medication Response (PGx Gene Test) sample report here.
What drugs does the Cardiac Medication Response DNA Test cover?
4U Health’s Cardiac Medication Response Test assesses the effectiveness of 15 common medications typically prescribed to enhance cardiovascular health. This test can identify potential side effects of cholesterol and blood pressure medications, as well as determine which heart medicines are most suitable for your specific genetic profile.
Discover how your body is likely to metabolize this extensive list of blood pressure medicines (Carvedilol, Metoprolol, Nebivolol, Propranolol, and More) cholesterol medicines (Atorvastatin, Pravastatin, Rosuvastatin, Simvastatin, and more) Plavix, and Warfarin. Use your results to learn which medicines may cause a good therapeutic or bad adverse outcome. For more information on which drugs this test covers, view full list of medications here.
What's a medication response pharmacogenomics (PGx) gene test?
Our cardiac pharmacogenomics (PGx) test provides essential information on 13 genes which may affect metabolism and response to cardiovascular drugs. Clinicians can use the personalized information provided with this PGx test to help select the best cardiac medication and dose for an individual patient, limiting potential adverse drug reactions.
Drug Metabolism Genotyping
Also known as pharmacokinetics, this analysis predicts the body’s impact on a drug. Its purpose is to determine patient-specific genetic variants that may influence the function of drug-metabolizing enzymes. It shows whether a patient is an ultrarapid metabolizer, extensive metabolizer, intermediate metabolizer, or poor metabolizer of a medication. Understanding your metabolizer phenotype is important, as it indicates how much of a drug may be active in the body to produce either therapeutic or toxic effects.
Drug Response Genotyping
Also known as pharmacodynamics, this analysis describes a drug’s predictive impact on the body. It considers the likelihood of a drug producing the desired therapeutic effect by identifying patient-specific genetic variants involved in how medications work. This can indicate the likelihood of a good (therapeutic) or bad (adverse) drug response.
What's a drug-induced disease?
Clinicians prescribe medications to treat disease or alleviate symptoms. The last thing you might expect is that a prescribed medication may do more harm than good. An adverse drug reaction (ADR) refers to the unintended side effects of a prescribed medication. A drug-induced disease occurs when an ADR warrants a patient consulting a doctor or getting hospitalized.
ADRs and drug-induced diseases are a reality. FDA studies estimate that 7% of hospitalized patients have a severe adverse drug reaction.2 Drugs are approved by the FDA for use only if their potential benefits far outweigh the risks involved. But it’s important to note not all people react similarly to a drug. A particular medicine may benefit some people while causing others potentially life-threatening unintended side effects.
A drug response test like this alerts patients and guides clinicians through the practice of personalized medicine. It allows prescribers to empirically select the best medications based on a patient’s unique genetic traits. This test may increase the likelihood of an optimal therapeutic outcome and limit the chances of an adverse drug reaction.
What's personalized pharmacy therapy?
One of the transformative trends in medicine is personalized pharmacy therapy. With the advent of medication response PGx tests, physicians and pharmacists alike can individualize a patient’s drug therapy consistent with that patient’s unique genetic makeup.
Our Cardiac Medication Response (PGx Gene Test) offers personalized medication guidance for 15 common drugs used to treat cholesterol, blood pressure, and other heart conditions. This test assists physicians in selecting the most suitable prescription medicines for individual patients, taking into account known drug-to-gene potential interactions.
Does this pharmacogenetics test include result explanation?
This state-of-the-art genetic test includes at no additional charge physician oversight throughout the entire testing process. Your report will give you the information necessary to have an informed discussion with your physicians and pharmacists to get the most out of your results.
What genes does the PGx Cardiac Medication Response Test analyze?
This test provides an analysis of 13 genes to identify 15 medications often used to help improve cardiovascular health for potential genetic induced adverse drug reactions and side effects.
Analyzes 13 Genes:
Apolipoprotein E, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, Factor II, Factor V Leiden, ITGB3, LPA, MTHFR, SLCO1B1, and VKORC1.
What factors commonly influence the body's response to a medication?
Multiple factors influence how a person reacts to a drug including:
- Genetics
- Age
- Allergies
- Medical History
- Weight and Body Size
Who should not take this PGx test?
The Cardiac Medication Response (PGx Gene Test) is not suitable for the following groups of people:
- Specimens collected in New York State
If you’re experiencing a severe adverse drug reaction, such as difficulty breathing, vision problems, hives, fever, or vomiting, we recommend you speak with your healthcare provider right away.
Can I buy now and use this Pharmacogenetics test later?
Test now or later. This at-home DNA test kit must be used by its expiration date – August 31, 2024. That’s great news if you are buying now but want to test yourself in the future or gifting to a friend or family member for later use.
Can I gift this PGx test to a friend or family member?
All 4U Health tests are eligible for gifting. In fact, they make great presents. The recipient who receives your gift will simply open the kit, register it, and follow the collection instructions. Within a few days of sending to the lab, your friend or family member will receive secure electronic HIPAA compliant results all thanks to your generosity.
Where is my DNA lab test performed?
4U Health tests meet national standards and are as accurate as services provided in a doctor’s office or hospital. We only work with the highest quality CLIA certified laboratories and health experts. All testing complies with state and federal regulations. And our clinicians provide medical oversight throughout the entire process.
How is my privacy protected?
Rest assured; HIPAA security standards protect your data every step of the way while determining your gene to drug responses. Keeping your confidential data secure is our number one priority. We only share your information when required to deliver our products and services or where we are legally obligated to do so. Your results are securely protected and available for review in your online portal; always secure but easily accessible only to you.
Will my Medication Response PGx Test be covered by insurance?
Many physicians don’t routinely order a medication response PGx Gene test. That’s because DNA tests like this often require pre-authorization from insurance carriers. If denied, patients with insurance coverage may face unexpected medical bills often in excess of a thousand dollars.
With 4U Health you pay a fair price upfront and receive no surprise medical bills. 4U Health is not enrolled in Medicare or any other private insurance network. This test is not eligible for Medicare or any other federal or state-funded insurance program reimbursement.
What are common heart medication side effects?
Some side effects of heart medicines stem from adverse drug-to-gene interactions, meaning a drug tolerated well by one individual may not be as well-tolerated by another due to differences in genetic makeup. Additionally, certain side effects can result from normal drug metabolism. Here is a list of 15 common heart medications along with some of their well known associated side effects:
(Lipitor®) Atorvastatin Side Effects
Common (Lipitor®) Atorvastatin Side Effects3:
- Arthralgia
- Diarrhea
- Pharyngitis
- Dyspepsia
- Pain
- Urinary tract infection
- Nausea
- Skin rash
- Myalgia
- Muscle spasm
- Dizziness
- Insomnia
- Musculoskeletal pain
Atorvastatin and Lipitor® side effects may rarely cause muscle problems:
Please inform your doctor immediately if you experience any of the following symptoms during treatment, especially if they persist after stopping the medication.
- Muscle pain/tenderness/weakness
- Signs of kidney problems
Lipitor® and Atorvastatin side effects may also rarely cause liver problems:
If you notice any of the following rare but serious side effects, notify your doctor promptly.
- Yellowing eyes/skin
- Dark urine
- Severe stomach/abdominal pain
- Persistent nausea/vomiting
(Lipitor®) Atorvastatin allergic reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Atorvastatin allergic reaction.
- Rash
- Itching/swelling
- Severe dizziness
- Trouble breathing
Other things to note about Atorvastatin (Lipitor®):
A very small number of people taking this medication may experience mild memory problems or confusion. If these rare effects occur, consult your doctor.
Rarely, this medication may cause or worsen diabetes. Discuss the benefits and risks with your doctor.
(Coreg®) Carvedilol Side Effects
Common (Coreg®) Carvedilol Side Effects4:
If any of these common (Coreg®) Carvedilol side effects persist or worsen, inform your healthcare provider promptly.
- Bradycardia
- Orthostatic hypotension
- Hypotension
- Back pain
- Dizziness and/or lightheadedness
- Drowsiness
- Fatigue
- Paresthesia
- Peripheral edema
- Weight gain
- Dyspnea
- Diarrhea
- Hyperglycemia
- Hypercholesterolemia
- Impotence
- Anemia
- Purpura
- Thrombocytopenic disorder
- Depression
- Blurred vision
- Atrioventricular block
- Pharyngitis
Serious (Coreg®) Carvedilol Side Effects:
Seek immediate medical attention if you experience any of these serious (Coreg®) Carvedilol side effects.
- Very slow heartbeat
- Severe dizziness
- Fainting
- Unusual weakness
- Signs of kidney problems
- Numbness/tingling of the hands/feet
- Blue fingers/toes
- Easy bruising/bleeding
- Mental/mood changes
- Seizures
Heart Failure Symptoms:
Although (Coreg®) Carvedilol may be prescribed for heart failure, some individuals may experience new or worsening symptoms, particularly at the onset of treatment. Notify your doctor promptly if you have any of the following new symptoms.
- Shortness of breath
- Swelling ankles/feet
- Unusual tiredness
- Unusual/sudden weight gain
(Coreg®) Carvedilol Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Carvedilol allergic reaction.
- rash, itching/swelling, severe dizziness, or trouble breathing.
- Itching/swelling
- Severe dizziness
- Trouble breathing
Additional Information About Carvedilol (Coreg®):
To minimize the risk of dizziness and lightheadedness, rise slowly when transitioning from sitting or lying down. The highest risk of dizziness is within one hour after taking the dose. Taking carvedilol with food and gradually increasing the dosage as directed by your doctor can help reduce this risk.
This medication may reduce blood flow to the extremities, leading to cold sensations in the hands and feet. Smoking may exacerbate this effect. Dress warmly and refrain from tobacco use.
Plavix Side Effects (Clopidogrel)
Check with your doctor immediately if any of the following side effects occur while taking clopidogrel.
More Common (Clopidogrel) Plavix Side Effects5:
- Collection of blood under the skin
- Deep, dark purple bruise
- itching, pain, redness, or swelling
Less Common (Clopidogrel) Plavix Side Effects:
- Bloody nose
- Bloody, black, or tarry stools
- Vomiting of blood or material that looks like coffee grounds
Rare (Clopidogrel) Plavix Side Effects:
- Bleeding in the eye
- Confusion
- Headache, sudden, severe, and continuing
- nausea and vomiting
(Clopidogrel) Plavix Gene to Drug Warning:
The effectiveness of clopidogrel hydrogen sulfate results from its antiplatelet activity, which is dependent on its conversion to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19. Clopidogrel hydrogen sulfate at recommended doses forms less of the active metabolite and so has a reduced effect on platelet activity in patients who are homozygous for nonfunctional alleles of the CYP2C19 gene, (termed “CYP2C19 poor metabolizers”). Tests like 4U Health’s Cardiac PGx DNA Kit are available to identify patients who are CYP2C19 poor metabolizers. Medical providers should consider use of another platelet P2Y12 inhibitor in patients identified as CYP2C19 poor metabolizers by PGx testing.
(Tambocor®) Flecainide Side Effects
Common (Tambocor®) Flecainide Side Effects6:
Tell your healthcare provider if any of the following or other side affects appear after taking (Tambocor®) Flecainide and are severe or don’t go away.
- Constipation
- Dizziness
- Headaches
- Stomach pain
- Tremors
- Vision changes
- Weakness
Serious (Tambocor®) Flecainide Side Effects
Tell your healthcare provider immediately if you experience any of these symptoms after taking (Tambocor®) Flecainide.
- Chest pain
- Confusion
- Chronic Cough, or a cough that produces mucus containing blood
- Extreme fatigue (tiredness)
- Fainting
- Fast or pounding heartbeat
- Flu-like symptoms, including fever
- Nausea or loss of appetite
- Shortness of breath
- Swelling in the hands, feet or lower legs
- Sudden weight gain
- Unusual bleeding or bruising
- Yellowish skin or eyes
(Tambocor®) Flecainide Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious (Tambocor®) Flecainide allergic reaction.
- Itchy skin
- Swelling of the face, lips, tongue or throat
- Wheezing when you breathe
(Lescol®) Fluvastatin Side Effects
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
More Common (Lescol®) Fluvastatin Side Effects7:
- Stomach discomfort.
Less Common (Lescol®) Fluvastatin Side Effects:
- Mild memory problems
- Confusion
- May cause or worsen diabetes
- Muscle pain/tenderness/weakness (especially with fever or unusual tiredness)
- Signs of kidney problems (such as change in the amount of urine)
- Signs of liver problems (such as nausea/vomiting that doesn’t stop, yellowing eyes/skin, dark urine, stomach/abdominal pain)
(Lescol®) Fluvastatin Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious (Lescol®) Fluvastatin allergic reaction.
- Rash, itchy skin
- Severe dizziness
- Swelling of the face, lips, tongue or throat
- Trouble breathing or wheezing when you breathe
This list does not encompass all potential Lescol side effects. Should you experience any other effects not mentioned here, please reach out immediately to your doctor or pharmacist for guidance.
(Mevacor®) Lovastatin Side Effects
More Common (Mevacor®) Lovastatin Side Effects8:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Pain in your stomach area
- Nausea
- Heartburn
- Constipation
- Headache
- Weakness/lack of energy
- Muscle pain
- Memory loss/forgetfulness
- Confusion
- Inability to fall asleep
Serious (Mevacor®) Lovastatin Side Effects
Tell your doctor right away if you have serious (Mevacor®) Lovastatin side effects.
- Muscle problems: Symptoms can include unexplained muscle pain, muscle tenderness, muscle weakness
- Liver problems: Symptoms can include dark-colored urine, yellowing of your skin or whites of your eyes
- Stomach problems: Symptoms can include pain in the upper right part of your stomach area, nausea, loss of appetite
- Central nervous system problems: Symptoms can include lack of energy, weakness, extreme tiredness
- Skin problems: Symptoms can include rash, hives, itching
- Bleeding problems: Symptoms can include unusual bleeding or bruising
- Flu-like symptoms: Symptoms can include fever, body aches, tiredness, cough
- Hoarseness
(Mevacor®) Lovastatin Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious (Mevacor®) Lovastatin allergic reaction.
- trouble breathing or swallowing
- swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- rash, hives, itching
This list does not encompass all potential Mevacor® side effects. Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible Lovastatin side effects and allergy symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Lovastatin.
(Lopressor®, Toprol®) Metoprolol Side Effects
Common side effects of Metoprolol9:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Nausea
- Vomiting
- Dry mouth
- Gas
- Heartburn
- Diarrhea
- Constipation
- Dizziness
- Tiredness
- Depression
- Decreased sex drive, impotence
- Difficulty having an orgasm
- Headache
- Drowsiness
- Tiredness
- Sleep problems (insomnia)
- Anxiety
- Nervousness
- Rash
Serious Metoprolol Side Effects
Tell your doctor right away if you have serious (Lopressor®, Toprol®) Metoprolol side effects.
- Wheezing
- Shortness of breath
- Swelling
- Irregular rapid heartbeats
Metoprolol Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious (Lopressor®, Toprol®) Metoprolol allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
(Lopressor®, Toprol®) Metoprolol Warning:
Metoprolol (Lopressor®, Toprol®) is primarily metabolized by CYP2D6. Metoprolol is a racemic mixture of Rand S- enantiomers, and when administered orally, it exhibits stereo selective metabolism that is dependent on oxidation phenotype. CYP2D6 is absent (poor metabolizers) in about 8% of Caucasians and about 2% of most other populations. Poor CYP2D6 metabolizers exhibit several-fold higher plasma concentrations of Metoprolol than extensive metabolizers with normal CYP2D6 activity thereby decreasing Lopressor’s cardioselectivity.
This list does not encompass all potential side effects, allergies and warnings for Metoprolol. Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Metoprolol (Lopressor).
Nebivolol Side Effects
Common side effects of Nebivolol (Bystolic®)10:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Headache (6-9%)
- Tiredness (2-5%)
- Dizziness (2-4%)
- Diarrhea (2-3%)
- Nausea (1-3%)
Severe side effects of Nebivolol (Bystolic®)
Tell your doctor right away if you have serious Nebivolol side effects.
- Chest pain
- Stomach pain
- Swelling in arms or legs
- Trouble sleeping
- Shortness of breath
- Rash
- Tingling sensation
This list does not encompass all potential side effects, allergies and warnings for Nebivolol (Bystolic®). Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Nebivolol (Bystolic®).
Pitavastatin Side Effects
Common side effects of Pitavastatin (Livalo®)11:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Back pain
- Constipation
- Diarrhea
- Muscle aches
- Pain in your arms or legs
Severe side effects of Pitavastatin (Livalo®)
Tell your doctor right away if you have serious Nebivolol side effects.
- Muscle problems: Symptoms can include, severe muscle pain, muscle tenderness, muscle weakness
- Kidney problems: Symptoms can include tiredness, confusion, nausea, shortness of breath, swelling (of your legs, ankles, or feet), decreased urination
- Liver problems: Symptoms can include jaundice (yellowing of your skin or the whites of your eyes), itching, pain in the upper right side of the stomach area, nausea, vomiting, loss of appetite, dark-colored urine, pale-colored or dark tarry stools, tiredness, bruising easily
Pitavastatin (Livalo®) Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Pitavastatin allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential Pitavastatin (Livalo®) side effects and allergic reactions. Should you experience any other effects not mentioned here, please reach out immediately to your doctor or pharmacist for guidance.
Pravastatin Side Effects
Common side effects of Pravastatin (Pravachol®)12:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Headache
- Dizziness
- Feeling tired or weak
- Diarrhea
- Upset stomach or throwing up
- Nose and throat irritation
- Runny nose
- Stuffy nose
- Cough
Severe side effects of Pravastatin (Pravachol®)
Tell your doctor right away if you have serious Nebivolol side effects.
- Chest pain
- Change in eyesight
- Not able to pass urine or change in how much urine is passed
- Muscle pain, tenderness, or weakness. Sometimes, a very bad muscle problem may happen that may lead to kidney problems. Rarely, deaths have happened in people who get these problems when taking drugs like this one. Call your doctor right away if you have muscle pain, tenderness, or weakness that is not normal (with or without fever or feeling out of sorts). Call your doctor right away if you have muscle signs that last after your doctor has told you to stop taking pravastatin.
- Very bad and sometimes deadly liver problems have happened with pravastatin. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
Pravastatin (Pravachol®) Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Pravastatin allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Pravastatin (Pravachol®). Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Pravastatin (Pravachol®).
Rythmol Side Effects (Propafenone)
Severe side effects of Rythmol (Propafenone)13:
- New or worsening heartbeat pattern. Call your doctor at once if you have fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out)
- Shortness of breath (even with mild exertion)
- Swelling in your arms or legs
- Sudden weight gain
- Fever, chills, sore throat
- Irregular heartbeats
- Nausea, vomiting, constipation
- Headache, dizziness, tiredness
- Unusual or unpleasant taste in your mouth
Rythmol Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Rythmol (Propafenone) allergic reaction.
- trouble breathing or swallowing
- swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Rythmol (Propafenone). Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Rythmol (Propafenone).
(Hemangeol®, Inderal®, InnoPran®, Propranolol HCl Intensol®) Propranolol Side Effects
Common side effects of Propranolol14:
If any of these effects last or get worse, tell your doctor or pharmacist promptly.
- Headaches
- Feeling tired, dizzy or weak
- Cold fingers or toes
- Feeling or being sick (nausea or vomiting), or diarrhoea
- Stomach pain
Severe side effects of Propranolol (Hemangeol®, Inderal®, InnoPran®, Propranolol HCl Intensol®)
Tell your doctor right away if you have serious Propranolol side effects.
- Signs of liver problems: The whites of your eyes turn yellow, your skin turns yellow, or you have pale poo or dark pee
- Signs of low numbers of platelets in your blood (thrombocytopenia): You get nosebleeds that last for more than 10 minutes, unexplained bruising, or you bruise more easily than usual
Propranolol Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Propranolol allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Propranolol (Hemangeol®, Inderal®, InnoPran®, Propranolol HCl Intensol®). Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Propranolol.
Crestor® (Rosuvastatin) Side Effects
Common side effects of Crestor® (Rosuvastatin)15:
Most frequent adverse reactions (rate ≥ 2%) include;
- Headache
- Myalgia (muscle pain)
- Abdominal pain
- Asthenia
- Nausea
Common side effects of Crestor® (Rosuvastatin)15:
Most frequent adverse reactions (rate ≥ 2%) include;
- Headache
- Myalgia (muscle pain)
- Abdominal pain
- Asthenia
- Nausea
Severe side effects of Crestor® (Rosuvastatin)
- Signs of liver problems: The whites of your eyes turn yellow, your skin turns yellow, or you have pale poo or dark pee
- Skeletal muscle problems: Immediately report to your medical provider unexplained muscle pain, tenderness, or weakness as soon as they appear
Crestor® (Rosuvastatin) Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Rosuvastatin allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Crestor® (Rosuvastatin). Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Crestor® (Rosuvastatin).
(Zocor®) Simvastatin Side Effects
Common (Zocor®) Simvastatin side effects16:
Most frequent adverse reactions (rate ≥ 2%) include;
- Headache
- Abdominal pain
- Constipation
- Nausea
- Upper respiratory infection
- Urinary tract infection
- Itchy skin
Severe side effects of Simvastatin (Zocor®)
Tell your doctor right away if you have serious Simvastatin side effects.
- Dizziness and falls
- Fast or irregular heartbeat
- Muscle pain or damage
- Liver damage
- Increased blood glucose (sugar)
- Forgetfulness or memory impairment
Simvastatin Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Simvastatin allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Simvastatin. Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Simvastatin (Zocor®).
Warfarin Side Effects
Common (Coumadin®) Warfarin side effects17:
Bleeding is the most common side effect of warfarin. Call your doctor at once if you have any signs of bleeding such as:
- Sudden headache
- Feeling very weak or dizzy
- Swelling, pain, unusual bruising
- Bleeding gums
- Bleeding from wounds or needle injections that will not stop
- Nosebleeds
- Heavy menstrual periods or abnormal vaginal bleeding
- Blood in your urine
- Bloody or tarry stools
- Coughing up blood
- Vomit that looks like coffee grounds
Severe side effects of Warfarin (Coumadin®)
Blood clots resulting from the administration of warfarin have the potential to obstruct regular blood circulation, consequently increasing the risk of tissue necrosis or necessitating the amputation of the affected area. Tell your doctor right away if you have serious any of these serious Warfarin side effects.
- Pain, swelling, hot or cold feeling, skin changes, or discoloration anywhere on your body
- Sudden and severe leg or foot pain, foot ulcer, purple toes or fingers
Warfarin Allergic Reactions:
However rare, seek immediate medical attention if you notice any symptoms of a serious Warfarin allergic reaction.
- Trouble breathing or swallowing
- Swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Rash, hives, itching
This list does not encompass all potential side effects, allergies and warnings for Warfarin. Because drugs interact differently in each individual, we cannot guarantee that this information includes all possible symptoms. Consult a healthcare provider if you experience any concerning symptoms when taking Warfarin (Coumadin®).
Blood Pressure Medicine Side Effects
- Weakness, tiredness, drowsiness, or dizziness
- Erectile dysfunction
- Trouble sleeping
- Slow or fast heartbeat
- Skin rash, blistering, or peeling
- Feeling thirsty
- Cough
- Headache
This list does not encompass all potential side effects of blood pressure medicine. Please consult your medical provider for specific side effects associated with your particular prescribed blood pressure medicine.
Cholesterol Medicines Side Effects
- Diarrhea
- Constipation
- Nausea
- Stomach cramps
- Muscle soreness, pain, or weakness
- Vomiting
- Headache
- Dizziness
Pharmacogenetic Testing
Pharmacogenetic (PGx) testing offers valuable insights into potential drug-to-gene interactions, which may diminish medication effectiveness and heighten the likelihood of adverse events, particularly concerning the above mentioned medicines. However, it’s essential to emphasize the importance of consulting a healthcare provider for personalized guidance and effective management of any associated side effects to ensure optimal treatment outcomes. A PGx test report may often provide a physician with insights that can help personalize your medication management and avoid unnecessary trial and error prescribing.
Genetic Testing for Medication
PGx testing has revolutionized treatment selection for cholesterol, blood pressure, Plavix, Warfarin and other heart medications. By analyzing an individual unique genetic composition, PGx tests can help tailor prescriptions to minimize drug to gene side effects and maximize drug efficacy by selected the medicines that are most likely to achieve a good therapeutic outcome. Don’t settle for trial and error—personalize your medication regime with the precision medicine of a PGx test.
Still have questions about the test?
So you still have unanswered questions. No worries, we’d love to hear from you. Reach us by e-mail, phone or chat and we will do our best to provide answers so you can determine if this is the best test for you or your child.
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