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Comprehensive COVID-19 Antibody Test

Gain insight into your readiness to fight off a new COVID infection — without leaving home

COVID Antibody Comprehensive Test

$259

 

(2 to 3 tests at $249 each)

(4 to 5 tests at $239 each)

(6 or more   at $229 each)

 

One time purchase - Free Shipping - FSA/HSA Credit Card Payments Accepted

My Cart

The test you've been looking for! This is the only at-home test that checks for both nucleocapsid and spike antibodies made after an exposure or vaccination to COVID-19. This test also provides a numerical value that indicates the level of protective antibodies present in your body. Test now to gain valuable insight into your COVID antibody immune status.

  • Our best selling and most complete at-home COVID antibody test 
  • Checks for both spike and nucleocapsid COVID antibodies
  • Identifies if you had a previous COVID-19 infection
  • Detects antibodies exclusive to a past infection
  • Tests for COVID neutralizing antibodies from a prior vaccine or infection 
  • Provides your current COVID antibody score (numeric level)
  • For vaccinated and non-vaccinated individuals
  • FDA authorized for adults and children 5+
  • Easy finger prick blood drop sample
  • Simple to understand CLIA certified lab results

Note: If you simply want to confirm your COVID Antibody Score (level) and don't want to check for nucleocapsid antibodies that are exclusive to a prior COVID-19 infection, check out our COVID-19 Antibody Test With Antibody Score.

Why test

For the most common reasons individuals get tested for COVID antibodies, click on your vaccine status below.

Reasons non-vaccinated individuals get tested ––      Learn your COVID antibody immune status

––       Test to see if you had a previous COVID-19 infection

––       Confirm you made and still have naturally occurring protective nucleocapsid antibodies from a prior COVID-19 infection

––       Find out if you made and still have neutralizing spike antibodies from a past COVID-19 infection

––       Discover your COVID antibody score: knowing your level gives you an indication of the relative strength of your spike antibody results

––       Track your COVID Antibody Score to verify your antibody levels remain detectable over time

Reasons vaccinated individuals get tested
––       Learn your COVID antibody immune status: natural infection + vaccination antibodies are generally thought to provide the maximum protection against COVID-19


––       See if you had a previous COVID-19 infection

––       Confirm you made and still have protective naturally occurring nucleocapsid antibodies exclusive to prior COVID-19 infection

––       Find out if you made and still have neutralizing spike antibodies from a past COVID-19 vaccine and/or infection

––       Discover your COVID antibody score: knowing your level gives you an indication of the relative strength of your spike antibody results

––       Track your COVID Antibody Score to verify your antibody levels remain detectable over time

Note: Only a test like this that checks for nucleocapsid antibodies can tell a vaccinated person if they've had a previous COVID-19 infection.

What to expect

  • Order your test online and we'll have it delivered directly to your door
  • Easily self-collect your finger prick sample
  • Mail it to the lab for testing with the prepaid shipping label included in your kit
  • Within 2 to 5 days, view your secure digital results on your device of choice
  • Help along the way if you need it

Details

What's measured

This test checks for nucleocapsid and spike covid antibodies. It allows you to check if you have produced (and still have) antibodies from a prior COVID-19 infection and/or vaccine and provides a numeric antibody level that you can track over time.

When infected with COVID, your immune system typically makes specific antibodies to fight it. The nucleocapsid portion of this test exclusively confirms whether you made a protective immune response to a prior natural COVID infection, regardless of your vaccine status.

This test also allows you to verify your neutralizing spike COVID antibody status to confirm the body has produced and still has detectable COVID-19 antibodies form either a prior vaccine or infection. Furthermore, it provides a spike COVID Antibody Score that allows you the option to track for changes in your level of antibodies over time.


Easy at-home test collection kit

In as little as five minutes, collect your sample from the comfort and privacy of your home, mail it to our certified lab with prepaid shipping then receive your secure digital results within a few days. Your kit includes finger prick (tiny blood drop) sample collection supplies along with detailed instructions.

And parents we've got you covered — hospitals use this method of collection on newborns; it's the least intrusive and painless way to acquire a blood sample.


Approved for indivduals 5-years-old and over

Understanding your child’s antibody status gives you powerful insight as to whether an unvaccinated child had a prior or recent COVID-19 infection and already has some level of antibodies and protection against COVID-19, or to check whether antibodies from a previous vaccine or infection remain detectable over time. This test is approved for parents to easily collect a fingerstick dried blood spot (DBS) specimen from a kid 5-years-old and older.

Adults 18-years-old and over may self collect their own specimens for this test.


Discreet packaging

Your mail-in antibody test kit is delivered in a plain envelope for a confidential testing experience insuring your medical privacy.


Certified lab results

You can expect timely, secure electronic results delivered to you in just a few days. The best part is we only work with federal and state-certified laboratories. This means your results are of the highest quality, and you can confidently share them with to any clinician.


For a healthier tomorrow, get answers today

Regardless of your vaccination status, whether your healthy or more at risk with pre-existing conditions, use this test today to better understand how ready your immune system is to fight off a new COVID-19 exposure.

 

For context, your immune system typically makes antibodies as a protective response to a natural infection. It can also safely learn to make antibodies through a COVID vaccine. Once you have antibodies to a particular disease either thru prior infection or vaccination, including COVID-19, antibodies usually provide increased protection from severe disease, hospitalization and death. But keep in mind, if an individual was previously infected or vaccinated, they might not have produced antibodies — not everybody does. Also, antibodies fade over time, so if an individual were infected or vaccinated some time ago, they may now have disappeared. This is why many individuals choose a COVID antibody test — to confirm they made antibodies to a COVID-19 infection or vaccine and for the peace of mind knowing whether their antibodies remain robust and detectable over time. 

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                         www.4uhealth.com

COVID Antibody Comprehensive Test

$259

 

(2 to 3 tests at $249 each)

(4 to 5 tests at $239 each)

(6 or more   at $229 each)

 

One time purchase - Free Shipping - FSA/HSA Credit Card Payments Accepted

My Cart

How It Works

How It Works

Order Your Test

Order online and have your COVID-19 antibody test kit express delivered in 1 to 2 days directly to your door, for a private testing experience.

Order Your Test

Order online and have your COVID-19 antibody test kit express delivered in 1 to 2 days directly to your door, for a private testing experience.

Collect Your Sample

Simply self collect your sample from the comfort of home. Return free of charge to the lab with the prepaid shipping label provided. 

Collect Your Sample

Simply self collect your sample from the comfort of home. Return free of charge to the lab with the prepaid shipping label provided. 

Receive your results

Usually within 2 to 5 days of your sample arriving at the lab, receive secure electronic results on your device of choice.

Receive your results

Usually within 2 to 5 days of your sample arriving at the lab, receive secure electronic results on your device of choice.

Get physician support

We’ve got you covered. Your test is ordered by a physician Health Consultant licensed in your state and comes with oversight to ensure the highest quality service.

Get physician support

We’ve got you covered. Your test is ordered by a physician Health Consultant licensed in your state and comes with oversight to ensure the highest quality service.

What our customers are saying

what our customers are saying

Wanted To Learn if I Ever Had Covid-19. Maty – Santa Fe, NMOctober 1, 2022

Got this test to learn if I ever had Covid. I did and also learned my antibody level. I’m so relieved I already beat Covid. This test was worth every penny to me. Love 4U Health 110%.

Immunocompromised. Dora – Dublin, OHSeptember 29, 2022

Test worked out well for me but wish my result findings were different. Had a terrible Covid infection at the beginning of the summer. I’m now a Covid long-hauler. Got this test because I’m immune compromised and it confirmed my worst fears. Tested positive for natural antibodies from my prior infection but my antibody level was almost nonexistent. I’m going to discuss my results with my doc because I was vaxed and infected and still have almost no protective antibodies. If your immune compromised, I highly recommend you test yourself before you get sick. Wish me luck!

Great Lab Test. John – Chicago, ILSeptember 28, 2022

I loved my results. So easy to understand. Thanks for providing this great service!

Illuminating, Totally Worth It. Lauren – Portland, ORSeptember 23, 2022

I collected my sample at home with this Covid antibody test and mailed it back to the lab. In 2 days I found out I had a previous Covid-19 infection, learned I had natural nucleocapsid antibodies and received my spike antibody level that showed I have good levels. I’m going to retest in 3 months again to see if my levels still look good then.

Legit Company. Liz – San Francisco, CASeptember 15, 2022

Have no fear, this company is legit. Was a little concerned ordering because this was the first time I ever purchased an online lab test. I’m very happy with my 2 covid antibody kits that arrived in just two days. The kit is actually pretty cool.

Still have questions

Still have questions

Not sure if this test is best for you? See our most frequently asked questions below or join our other satisfied customers who reach out to us via the chat button on the bottom right of your screen. We're glad to explain our COVID Antibody testing options and help answer your unique questions. Our goal is to make sure you select the best at-home test to get the most out of your COVID antibody results. 

What’s included in the At-Home COVID-19 Antibody Test kit?• Pre-paid shipping both ways
• Easy to follow instructions
• An at-home blood drop collection kit (via an easy finger prick)
      -  Blood spot sample card
      -  Two finger prick lancets
      -  Two alcohol pads
      -  Two gauze pads
      -  Two bandages
      -  Biohazard transport bag
• Return protective envelope to mail sample to the lab for testing
• Secure electronic results
• Physician oversight throughout the entire testing process
• Help along the way if you need it

What are COVID antibodies?COVID Antibodies are proteins created by your immune system that help you fight off a COVID-19 infection. They are made after you've been infected by the SARS-CoV-2 virus or have been vaccinated against an infection. 

Antibodies help clear a viral infection and may protect you from getting the same infection for some period of time afterward. How long this protection lasts is different for each disease and each person. At this time, researchers do not know whether the presence, or at what quantity antibodies incur immunity to COVID-19; or if they do, how long immunity will last. Howbeit, per the CDC if a reinfection happens, having antibodies plays an important role in helping prevent severe illness, hospitalizations, and death.

Why should I, or my child, get tested for COVID antibodies?A COVID antibody test, sometimes referred to as a COVID serology test, looks for antibodies in your blood that fight the virus that causes COVID-19. In both children and adults, COVID antibody testing can help identify if you were exposed to SARS-CoV-2 coronavirus, and if exposed, check whether or not your body has produced a protective immune response. 

COVID antibody tests may be helpful if you want to know whether your body has current detectable levels of COVID-19 antibodies because:

•  You were never diagnosed with COVID-19 and are looking to determine if you may have been previously infected with the virus.

•  You have previously tested positive for COVID-19 and want to know if your body has produced a protective immune response.

•  You received a COVID-19 vaccine and want to know if your body has produced an immune response.

•  You want to intermittently track if antibody levels remain detectable over time.

What is a COVID Antibody Score? The spike portion of your result is a semiquantitative COVID-19 Antibody Test that provides a Detected or Not-detected finding along with a COVID Antibody Score, a numerical value of your antibody level. Knowing your level gives you an indication of the relative strength of your spike antibody results. Follow-up testing of your COVID Antibody Score can show changes over time in your immune response to previous COVID-19 infections and or vaccines; so long as you use the same test to evaluate for fluctuations in your antibody levels.

Can you test positive for antibodies if you never had symptoms of COVID-19 or never received a COVID-19 vaccine? You may test positive for antibodies even if you have never had symptoms of COVID-19 or have not yet received a COVID-19 vaccine. This can happen if you had an infection without symptoms, which is called an asymptomatic infection.

A study published in JAMA Network Open found that, globally, more than 40% of confirmed COVID-19 cases were asymptomatic. Moreover, the Mayo Clinic reports up to 50% of children and adolescents might have COVID-19 with no symptoms.

When should I, or my child, get tested for COVID antibodies?It usually takes between 1 to 3 weeks after infection or vaccination for the body to make COVID-19 antibodies. To avoid recollection, a COVID antibody test should ideally be administered no sooner than 21 days after a suspected exposure or immunization.

What effect does vaccination have on COVID antibodies?COVID-19 vaccines teach your body to produce antibodies to the spike proteine of SARS-CoV-2, to fight infection from the virus that causes COVID-19. If you get an antibody test after receiving a vaccine, you might test positive by some (but not all) antibody tests. This depends on which type of antibody the specific test detects.

What are the two main types of COVID antibody tests?This test checks for both spike protein IgG COVID antibodies and nucleocapsid protein IgG antibodies. This is our most complete COVID antibody test. 

Spike Protein IgG Antibody Tests:
A spike protein COVID-19 IgG antibody test detects an immune response to a previous COVID-19 infection or vaccine. It is useful in evaluating for protective antibodies against the SARS-CoV-2 virus, whether the antibodies were acquired from a previous COVID-19 infection or vaccine immunization. This semi-quantitative spike protein IgG COVID-19 antibody test provides a Detected/Not Detected result along with a COVID Antibody Score (level).

Nucleocapsid IgG Antibody Tests: A nucleocapsid protein COVID-19 IgG antibody test only detects an immune response to a previous Covid-19 infection. It is especially useful to help evaluate whether a vaccinated individual had previous exposure to SARS-CoV-2, but also used by non-vaccinated individuals too. Keep in mind that (a) nucleocapsid proteins may not be as long-lasting, (b) IgG antibodies develop to spike but not to the nucleocapsid viral protein in many asymptomatic and light COVID-19 cases and (c) are not produced by vaccines authorized in the United States. If you're vaccinated and want to confirm you had a previous COVID infection, you can check out our Comprehensive COVID Antibody Test that exclusively evaluates for antibodies from a prior COVID illness.

What is the primary purpose of the spike protein component of the SARS-Co-V2 virus?The spike protein is found on the surface of SARS-CoV-2, the virus causing COVID-19.

Spike Protein's Role in Natural Infection
The key feature of the spike protein is to allow the virus to penetrate host cells within your body and cause infection. When SARS-CoV-2 enters the body, its spike protein acts as a key, gaining entry to the cell. The immune system responds by producing protective anti-spike antibodies that bind to the invading virus, blocking or neutralizing its effects.

Spike Protein's Role in Vaccination
Without the S protein, viruses like the novel SARS-CoV-2 would not be able to interact with host cells to cause infection. As such, the spike protein makes an ideal target for vaccines. All currently available COVID-19 vaccines in the United States currently target the immune system to produce a protective anti-spike antibody response.

The spike portion of this test will detect a protective immune response to a previous COVID-19 infection or vaccine and provide your antibody level.

What does a positive COVID antibody test result mean?A positive COVID antibody test result shows your blood sample demonstrated antibodies made from an immune response to either a previous infection or vaccination for the virus that causes COVID-19, and at the time of the test, the antibodies were still present circulating in the blood.

Some antibodies made for the virus that causes COVID-19 provide protection from getting infected. CDC is evaluating what degree of safety COVID antibodies provide and how long protection from antibodies might last. Although infection is possible after having produced antibodies from vaccination or prior infection, having antibodies plays an important role in helping prevent severe COVID-19 disease.

What does a negative COVID antibody test mean?A negative COVID antibody test result shows your blood sample demonstrated, at the time of collection, no detectable circulating antibodies to the SARS-CoV-2 coronavirus. A not-detected finding does not preclude the possibility of a previous vaccine or infection. If an individual was previously infected or vaccinated, they might not have produced spike protein antibodies - not everybody does. Also, antibodies fade over time, so if an individual were infected or vaccinated some time ago, they may now have disappeared.

How do I self-collect an At-Home Covid Antibody Test sample?To simplify and make COVID antibody testing less painful, 4U Health uses a fingerstick dried blood spot sample method as part of its self-collection kit. To learn how easy it is to collect a dried blood spot specimen and mail it to the lab for testing, you can view this self-collection instructions video.

Can I buy now and use this test later?Test now or later. Your self-collection test kit will arrive with an expiration date of at least 5 months from your order date. That’s great news if you are buying multiple kits for yourself or want to gift to a friend or family member for later use. All test samples must be collected and mailed by the expiration date on your kit. Our current lot of test kits expire on March 19, 2023.

Can I gift this test to a friend or family member?All 4U Health tests are eligible for gifting. In fact, they make great presents. The recipient who receives your gift will simply open the kit, register it, and follow the collection instructions. Within a few days of sending to the lab, your friend or family member will receive secure electronic HIPAA compliant results all thanks to your generosity.

If I know I have COVID antibodies, what should I do if I experience COVID-19 like symptoms?Any person, whether they have antibodies or not, should get a viral test to evaluate for a current infection if they have COVID-19 like symptoms or have a suspected or confirmed exposure to someone with COVID-19. For information about an at-home saliva PCR COVID-19 test option, click here.

What are common symptoms of COVID-19?Many people who are infected with COVID-19 are asymptomatic, meaning they do not experience symptoms. If you want to find out if you or your child had COVID-19, 4U Health’s at-home COVID-19 antibody test is a simple way to learn your antibody status. Symptomatic patients with COVID-19 often report a wide range of symptoms anywhere from 2 thru 14 days after exposure to the virus. If you have experienced one or more of the following symptoms, your likelihood of having had a COVID-19 infection is increased.

• Fever or chills
• Cough
• Sore throat
• Sinus congestion or runny nose
• Loss of taste or smell
• Shortness of breath or difficulty breathing
• Fatigue or general body weakenss
• Muscle or body aches
• Nausea or vomiting
• Diarrhea

When would this test not be helpful?A COVID antibody test may NOT be right for you if you are trying to diagnose COVID-19. Note, COVID antibody tests are not approved to diagnose for an active COVID-19 infection. A COVID antibody test only shows whether the body has developed an adaptive immune response to the virus as part of a prior infection or vaccine. To test for an active COVID-19 infection, click here.

You should not get a COVID antibody test if:
• You feel sick or have had a fever within the last 3 full days; please contact a healthcare provider.

• It is less than 10 days since you tested for and were diagnosed with COVID-19.

• You were directly exposed to COVID-19 in the past 14 days.

• It is less than 2 weeks since you had your complete vaccination for COVID-19.

• You live in New York State, Pennsylvania, or Maryland. This serology test is not available for self-collection in NY, PA or MD.

What is the FDA emergency authorization intended use of the COVID-19 Antibody Self-Collection Test?Covid antibody testing is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2, indicating recent or prior infection. The test provides semi-quantitative detection of IgG antibodies to SARS-CoV-2 in human fingerstick by dried blood spot (DBS) specimens. Antibody tests are self-collected at home by individuals age 18 years or older or collected by adults from individuals 5 years of age and older using the COVID-19 Self-Collected Antibody Test System. Home covid antibody test kits are ordered when appropriate by a healthcare provider licensed to practice medicine in the state where a specimen is self collected. The telehealth medical practitioner order is included in the cost of the test.

At this time, it is unknown for how long antibodies persist following infection (or vaccination) and if the presence of antibodies confers protective immunity.

This at home self collection serology test system has not been FDA cleared or approved but has been authorized for emergency use by the FDA. This test system has been authorized only for detecting IgG antibodies to SARS-CoV-2, not for any other viruses or pathogens.

The emergency use of this at home self collection serology test system is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. § 360bbb-3(b)(1), unless the declaration is terminated or authorization is revoked sooner.

Where is my lab test performed?4U Health offers at home collection tests with mailing to certified laboratories. The performance of all testing on your samples complies with state and federal regulations. We only work with the best laboratories and health experts. Your Health Consultant provides medical oversight. Our test meets nationwide standards and are as accurate as tests done and services provided in a doctor’s office or hospital.

The laboratories we work with are CLIA high complexity testing organizations at the forefront of infectious disease services.

How is my privacy protected?Rest assured; HIPAA web security protocols protect your data along every step of the way to finding out your COVID-19 antibody status. Keeping your personal data secure is important to us. We only share your information where required to deliver our products and services or where we have a legal basis to do so. Your results are securely protected and available for review online; always secure but easily accessible only to you.

Will my COVID-19 Antibody Self-Collection Kit be covered by insurance?Pay upfront and receive no surprise medical bills. For the privacy of our clients, 4U Health is not enrolled in Medicare or any other private insurance network. This test is not eligible for Medicare or any other federal or state-funded insurance program reimbursement.

Are there limitations to COVID-19 antibody tests? It usually takes between 1 to 3 weeks after infection or vaccination for the body to make COVID-19 antibodies. A false negative result may sometimes occur if you get an antibody test too soon after being exposed or vaccinated and your body has not yet made enough antibodies to be detected by the test. To help avoid a false negative result, a COVID antibody test should therefore be administered no sooner than 21 days after a suspected exposure or immunization.

Additionally, some immunocompromised individuals, often those with weakened immune systems due to a medical condition or certain medications, may not develop detectable levels of antibodies after exposure or vaccination.

Although rare, a false positive test result may occur if the test cross-reacts and detects antibodies from other coronaviruses you may have been exposed to, like the virus that causes the common cold.

To properly interpret your results, it's always advised you follow up with a healthcare provider, who can evaluate your medical history.

Can a COVID-19 antibody test be used to determine my immunity level? A COVID antibody test can help identify individuals who have developed an immune response after exposure to COVID-19 or vaccination.

Although infection is possible after having produced antibodies from vaccination or prior infection, having antibodies is thought to play an important role in helping prevent severe COVID-19 disease. The CDC advises it should not be used to determine the level of immunity or protection you have. Evidence is still being collected and studied to determine if antibodies, and at what level, provide protective immunity against SARS-CoV-2 (COVID-19) specifically.

Follow up with your healthcare provider for additional guidance on how to interpret your test results.

Can a patient's COVID antibody level be compared for interval changes to results produced from another lab (different lab test)? In reference to antibody numbers, please note there are no generally recognized international standardized units or antibody levels for COVID Antibody Tests allowed by the FDA at this time. As such, if you already had an antibody level from another test, it is generally advised you follow up with the same test by the same lab to evaluate for an interval change between two results. Again, it is generally not advised to compare an antibody numerical level from one type of COVID Antibody test to another different type of antibody level test for an interval change.

Follow up with your healthcare provider for additional guidance on how to interpret your test results, particularly how they may compare to previous results obtained from another test assay.

How do I contact 4U Health?We’d love to hear from you. Reach us by e-mail, phone or chat and we will do our best to answer your questions or concerns.

E-mail: help@4uhealth.com
Phone: 866-610-1200

What’s included in the At-Home COVID-19 Antibody Test kit?

• Pre-paid shipping both ways
• Easy to follow instructions
• An at-home blood drop collection kit (via an easy finger prick)
• Return protective envelope to mail sample to the lab for testing
• Secure electronic results
• Printable paper results to share with your doctor
• Physician oversight throughout the entire testing process
• Help along the way if you need it

What are COVID antibodies?

COVID Antibodies are proteins created by your immune system that help you fight off a COVID-19 infection. They are made after you have been infected by the SARS-CoV-2 virus or have been vaccinated against an infection. 

Antibodies help clear a viral infection and may protect you from getting the same infection for some period of time afterward. How long this protection lasts is different for each disease and each person. At this time, researchers do not know whether the presence, or at what quantity antibodies incur immunity to COVID-19; or if they do, how long immunity will last. Howbeit, per the CDC if a reinfection happens, having antibodies plays an important role in helping prevent severe illness, hospitalizations, and death.

Why should I, or my child, get tested for COVID antibodies?

A COVID antibody test, sometimes referred to as a COVID serology test, looks for antibodies in your blood that fight the virus that causes COVID-19. In both children and adults, COVID antibody testing can help identify if you were exposed to SARS-CoV-2 coronavirus, and if exposed, check whether or not your body has produced a protective immune response. 

 

COVID antibody tests may be helpful if you want to know whether your body has current detectable levels of COVID-19 antibodies because:

 

•  You were never diagnosed with COVID-19 and are looking to determine if you may have been previously infected with the virus.

 

•  You have previously tested positive for COVID-19 and want to know if your body has produced a protective immune response.

 

•  You received a COVID-19 vaccine and want to know if your body has produced an immune response.

 

•  You want to intermittently track if antibody levels remain detectable over time.

What is a COVID Antibody Score? 

The spike portion of your result is a semiquantitative COVID-19 Antibody Test that provides a Detected or Not-detected finding along with a COVID Antibody Score, a numerical value of your antibody level. Follow-up testing of your COVID Antibody Score can show changes over time in your immune response to previous COVID-19 infections and or vaccines; so long as you use the same test to evaluate for fluctuations in your antibody levels.

Can you test positive for antibodies if you never had symptoms of COVID-19 or never received a COVID-19 vaccine? 

You may test positive for antibodies even if you have never had symptoms of COVID-19 or have not yet received a COVID-19 vaccine. This can happen if you had an infection without symptoms, which is called an asymptomatic infection.

 

A study published in JAMA Network Open found that, globally, more than 40% of confirmed COVID-19 cases were asymptomatic. Moreover, the Mayo Clinic reports up to 50% of children and adolescents might have COVID-19 with no symptoms.

When should I, or my child, get tested for COVID antibodies?

It usually takes between 1 to 3 weeks after infection or vaccination for the body to make COVID-19 antibodies. To avoid recollection, a COVID antibody test should ideally be administered no sooner than 21 days after a suspected exposure or immunization.

What effect does vaccination have on COVID antibodies?

COVID-19 vaccines teach your body to produce antibodies to the spike proteine of SARS-CoV-2, to fight infection from the virus that causes COVID-19. If you get an antibody test after receiving a vaccine, you might test positive by some (but not all) antibody tests. This depends on which type of antibody the specific test detects.

What are the two main types of COVID antibody tests?

This test checks for both spike protein IgG COVID antibodies and nucleocapsid protein IgG antibodies. This is our most complete COVID antibody test.

This test checks for both spike protein IgG COVID antibodies and nucleocapsid protein IgG antibodies. This is our most complete COVID antibody test.

 

Spike Protein IgG Antibody Tests: A spike protein COVID-19 IgG antibody test detects an immune response to a previous COVID-19 infection or vaccine. It is useful in evaluating for protective antibodies against the SARS-CoV-2 virus, whether the antibodies were acquired from a previous COVID-19 infection or vaccine immunization. This semi-quantitative spike protein IgG COVID-19 antibody test provides a Detected/Not Detected result along with a COVID Antibody Score (level).

 

Nucleocapsid IgG Antibody Tests: A nucleocapsid protein COVID-19 IgG antibody test only detects an immune response to a previous Covid-19 infection. It is useful to help evaluate whether an individual had a previous exposure to SARS-CoV-2, with the limitations that (a) nucleocapsid proteins may not be as long-lasting, (b) IgG antibodies develop to spike but not to the nucleocapsid viral protein in many asymptomatic and light COVID-19 cases and (c) are not produced by vaccines authorized in the United States. If you're vaccinated and want to confirm you had a previous COVID infection, you'll need a nucleocapsid test. This is a qualitative nucleocapsid protein IgG COVID-19 antibody test that provides a Detected/Not Detected result.

What is the primary purpose of the spike protein component of the SARS-Co-V2 virus

The spike protein is found on the surface of SARS-CoV-2, the virus that causes COVID-19.

 

Spike Protein's Role in Natural Infection

The key feature of the spike protein is to allow the virus to penetrate host cells within your body and cause infection. When SARS-CoV-2 enters the body, its spike protein acts as a key, gaining entry to the cell. The immune system responds by producing protective anti-spike antibodies that bind to the invading virus, blocking or neutralizing its effects.

 

Spike Protein's Role in Vaccination
Without the S protein, viruses like the novel SARS-CoV-2 would not be able to interact with host cells to cause infection. As such, the spike protein makes an ideal target for vaccines. All currently available COVID-19 vaccines in the United States currently target the immune system to produce a protective anti-spike antibody response.


This is a spike protein IgG COVID antibody test and will detect a protective immune response to a previous COVID-19 infection or vaccine and provide your antibody level. This is also a nucleocapsid antibody test that confirms a prior COVID infection, regardless of your vaccine status.

What does a positive COVID antibody test result mean?

A positive COVID antibody test result shows your blood sample demonstrated antibodies made from an immune response to either a previous infection or vaccination for the virus that causes COVID-19, and at the time of the test, the antibodies were still present circulating in the blood.

 

Some antibodies made for the virus that causes COVID-19 provide protection from getting infected. CDC is evaluating what degree of safety COVID antibodies provide and how long protection from antibodies might last. Although infection is possible after having produced antibodies from vaccination or prior infection, having antibodies plays an important role in helping prevent severe COVID-19 disease.

What does a negative COVID antibody test mean?

A negative COVID antibody test result shows your blood sample demonstrated, at the time of collection, no detectable circulating antibodies to the SARS-CoV-2 coronavirus. A not-detected finding does not preclude the possibility of a previous vaccine or infection. If an individual was previously infected or vaccinated, they might not have produced spike protein antibodies - not everybody does. Also, antibodies fade over time, so if an individual were infected or vaccinated some time ago, they may now have disappeared.

How do I self-collect an At-Home Covid Antibody Test?

To simplify and make COVID antibody testing less painful, 4U Health uses a fingerstick dried blood spot sample method as part of its self-collection kit. To learn how easy it is to collect a dried blood spot specimen and mail it to the lab for testing, you can view the following self-collection instructions video.

Can I buy now and use this test later?

Test now or later. Your self-collection test kit will arrive with an expiration date of at least 6 months from your order date. That’s great news if you are buying multiple kits for yourself or want to gift to a friend or family member for later use. All test samples must be collected and mailed by the expiration date on your kit.

Can I gift this test to a friend or family member?

All 4U Health tests are eligible for gifting. In fact, they make great presents. The recipient who receives your gift will simply open the kit, register it, and follow the collection instructions. Within a few days of sending to the lab, your friend or family member will receive secure electronic HIPAA compliant results all thanks to your generosity.

If I know I have COVID antibodies, what should I do if I experience COVID-19 like symptoms?

Any person, whether they have antibodies or not, should get a viral test to evaluate for a current infection if they have COVID-19 like symptoms or have a suspected or confirmed exposure to someone with COVID-19. For information about an at-home saliva PCR COVID-19 test option, click here.

What are common symptoms of COVID-19?

Many people who are infected with COVID-19 are asymptomatic, meaning they do not experience symptoms. If you want to find out if you or your child had COVID-19, 4U Health’s at-home COVID-19 antibody test is a simple way to learn your antibody status. Symptomatic patients with COVID-19 often report a wide range of symptoms anywhere from 2 thru 14 days after exposure to the virus. If you have experienced one or more of the following symptoms, your likelihood of having had a COVID-19 infection is increased.

• Fever or chills
• Cough
• Sore throat
• Sinus congestion or runny nose
• Loss of taste or smell
• Shortness of breath or difficulty breathing
• Fatigue or general body weakenss
• Muscle or body aches
• Nausea or vomiting
• Diarrhea

When would this test not be helpful?

A COVID antibody test may NOT be right for you if you are trying to diagnose COVID-19. Note, COVID antibody tests are not approved to diagnose for an active COVID-19 infection. A COVID antibody test only shows whether the body has developed an adaptive immune response to the virus as part of a prior infection or vaccine. To test for an active COVID-19 infection, click here.

 

You should not get a COVID antibody test if:
• You feel sick or have had a fever within the last 3 full days; please contact a healthcare provider.

• It is less than 10 days since you tested for and were diagnosed with COVID-19.

• You were directly exposed to COVID-19 in the past 14 days.

• It is less than 2 weeks since you had your complete vaccination for COVID-19.

 

• You live in New York State, Pennsylvania, or Maryland. This serology test is not available for self-collection in NY, PA or MD.

 

• You are 4-years-old or younger.

What is the intended use of the COVID-19 Antibody Self-Collection Test?

Covid antibody testing is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2, indicating recent or prior infection. The test provides semi-quantitative detection of anti-spik IgG antibodies to SARS-CoV-2 and a quantitative detection of anti-nucleocapsid IgG antibodies to SARS-CoV-2  in human fingerstick by dried blood spot (DBS) specimens. Antibody tests are self-collected at home by individuals age 18 years or older or collected by adults from individuals 5 years of age and older using the COVID-19 Self-Collected Antibody Test System. Home covid antibody test kits are ordered when appropriate by a healthcare provider licensed to practice medicine in the state where a specimen is self collected. The telehealth medical practitioner order is included in the cost of the test.


At this time, it is unknown for how long antibodies persist following infection (or vaccination) and if the presence of antibodies confers protective immunity.


This at home self collection serology test system has not been FDA cleared or approved but has been authorized for emergency use by the FDA. This test system has been authorized only for detecting IgG antibodies to SARS-CoV-2, not for any other viruses or pathogens.


The emergency use of this at home self collection serology test system is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. § 360bbb-3(b)(1), unless the declaration is terminated or authorization is revoked sooner.

Where is my lab test performed?

4U Health offers at home collection tests with mailing to certified laboratories. The performance of all testing on your samples complies with state and federal regulations. We only work with the best laboratories and health experts. Your Health Consultant provides medical oversight. Our test meets nationwide standards and are as accurate as tests done and services provided in a doctor’s office or hospital.

 

The laboratories we work with are CLIA high complexity testing organizations at the forefront of infectious disease services.

How is my privacy protected?

Rest assured; HIPAA web security protocols protect your data along every step of the way to finding out your COVID-19 antibody status. Keeping your personal data secure is important to us. We only share your information where required to deliver our products and services or where we have a legal basis to do so. Your results are securely protected and available for review online; always secure but easily accessible only to you.

Will my COVID-19 Antibody Self-Collection Kit be covered by insurance?

Pay upfront and receive no surprise medical bills. 4U Health is not enrolled in Medicare or any other private insurance network. This test is not eligible for Medicare or any other federal or state-funded insurance program reimbursement.

Are there limitations to COVID-19 antibody tests? 

It usually takes between 1 to 3 weeks after infection or vaccination for the body to make COVID-19 antibodies. A false negative result may sometimes occur if you get an antibody test too soon after being exposed or vaccinated and your body has not yet made enough antibodies to be detected by the test. To help avoid a false negative result, a COVID antibody test should therefore be administered no sooner than 21 days after a suspected exposure or immunization.

 

Additionally, some immunocompromised individuals, often those with weakened immune systems due to a medical condition or certain medications, may not develop detectable levels of antibodies after exposure or vaccination.

 

Although rare, a false positive test result may occur if the test cross-reacts and detects antibodies from other coronaviruses you may have been exposed to, like the virus that causes the common cold.

 

To properly interpret your results, it's always advised you follow up with a healthcare provider, who can evaluate your medical history.

Can a COVID-19 antibody test be used to determine my immunity level? 

A COVID antibody test can help identify individuals who have developed an immune response after exposure to COVID-19 or vaccination.

 

Although infection is possible after having produced antibodies from vaccination or prior infection, having antibodies is thought to play an important role in helping prevent severe COVID-19 disease. The CDC advises it should not be used to determine the level of immunity or protection you have. Evidence is still being collected and studied to determine if antibodies, and at what level, provide protective immunity against SARS-CoV-2 (COVID-19) specifically.

 

Follow up with your healthcare provider for additional guidance on how to interpret your test results.

Can a patient's COVID antibody level be compared for interval changes to results produced from another lab (different lab test)? 

In reference to antibody numbers, please note there are no generally recognized international standardized units or antibody levels for COVID Antibody Tests allowed by the FDA at this time. As such, if you already had an antibody level from another test, it is generally advised you follow up with the same test by the same lab to evaluate for an interval change between two results. Again, it is generally not advised to compare an antibody level from one type of COVID Antibody test to another different type of antibody level test for an interval change, as there is no general standardized reporting units or levels between different covid antibody test assays at this time.

 

Follow up with your healthcare provider for additional guidance on how to interpret your test results, particularly how they may compare to previous results obtained from another test assay.

How do I contact 4U Health?

We’d love to hear from you. Reach us by e-mail, phone or chat and we will do our best to answer your questions or concerns.

 

E-mail: help@4uhealth.com

Phone: 866-610-1200

Covid Antibodie Self Collection Test Kit

COVID Antibody Comprehensive Test

$259

 

(2 to 3 tests at $249 each)

(4 to 5 tests at $239 each)

(6 or more   at $229 each)

 

One time purchase - Free Shipping - FSA/HSA Credit Card Payments Accepted

My Cart

Covid Antibodie Self Collection Test Kit

COVID Antibody Comprehensive Test

$259

 

(2 to 3 tests at $249 each)

(4 to 5 tests at $239 each)

(6 or more   at $229 each)

 

One time purchase - Free Shipping - FSA/HSA Credit Card Payments Accepted

My Cart

Let's get technical

Let's get technical

Can you provide links to technical documentation?
How do I view this antibody serology test’s FDA (EUA) authorization?

FDA Emergency Use Authorization. Updated June 24 2021. Accessed September 19, 2022.

How do I view this antibody serology test’s FDA fact sheet for recipients?

FDA Fact Sheet for Recipients. Updated April 5, 2021. Accessed September 19, 2022.

How do I view this antibody serology test’s fact sheet for healthcare providers?
FDA Fact Sheet for Healthcare Providers. Updated June 24, 2021. Accessed September 19, 2022.

How do I view a sample lab report?COVID-19 Antibody Sample Report.

Where can I find additional information about COVID-19 antibodies testing?
For additional information about COVID-19 antibody testing, visit the FDA website or CDC website.

Can you provide links to your most recent Wellness Blog articles on Covid-19?
View Our Wellness Blog For Healthy Living Topics
Wellness Blog

Recent Covid Articles
Top 10 COVID Antibody Questions. 4U Health. Updated March 8, 2022. Accessed September 19, 2022.

Best At-Home COVID Antibody Test. 4U Health. Updated March 7, 2022. Accessed September 19, 2022.

Natural Immunity for the Win! At-Home COVID Antibody Test Gets FDA EUA. 4U Health. Updated March 5, 2022. Accessed September 19, 2022.

Free Antiviral Pills for COVID-19 Positive People, President Biden Says. 4U Health. Updated March 2, 2022. Accessed September 19, 2022.

Younger Males Should Wait Longer Between COVID-19 Vaccines Over Myocarditis Risk, CDC Advises. 4U Health. Updated February 28, 2022. Accessed September 19, 2022.

Majority of Healthy Americans Can Ditch Masks, per New CDC Guidelines. 4U Health. Updated February 27, 2022. Accessed September 19, 2022.

BA.2 Omicron Subvariant Apparently Does Not Make People More Sick, South African Researchers Say. 4U Health. Updated February 25, 2022. Accessed September 19, 2022.

Omicron Name Used for Several Lineages of Coronavirus. 4U Health. Updated February 25, 2022. Accessed September 19, 2022.

BA.2 Omicron Appears More Dangerous, Researchers Say. 4U Health. Updated February 19, 2022. Accessed September 19, 2022.

Coronavirus Cases Fall After Record Breaking Omicron Surge. 4U Health. Updated February 24, 2022. September 19, 2022.

3rd Vaccine Booster Offers Strong Short-Term Protection Against Omicron, but Effectiveness Wanes, CDC Study Shows. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

New COVID-19 Monoclonal Antibody Treatment for Omicron Authorized by FDA. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

COVID Vaccines for Young Children, Ages 6 Months to 4 Years, Postponed. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

Highest-Risk COVID Patients Least Likely To Get Monoclonal Antibodies, Researchers Say. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

N95 Masks Offer Better Protection Against COVID Omicron Variant Than Cloth Face Coverings, CDC Says. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

BA.2 Subvariant More Contagious Than Original Omicron Variant, Denmark Study Finds. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

Omicron Evades Some, but Not All, Monoclonal Antibody Treatments, Study and FDA Say. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

Omicron Generally Causes Less Severe COVID-19 Disease, Multiple Studies Show. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

Saliva Covid Test Better Than Nasal Swabs To Detect Omicron, Study Says. 4U Health. Updated February 24, 2022. Accessed September 19, 2022.

FDA Authorizes & CDC Recommends Booster Shots for Older Teens. 4U Health. Updated December 9, 2021. Accessed September 19, 2022.

Omicron Has Extensive Escape of Pfizer Vaccine Protection, First Study On New Covid Variant Suggests. 4U Health. Updated December 8, 2021. Accessed September 19, 2022.

5 Reasons To Keep PCR Home Covid Test Kits on Hand. 4U Health. Updated December 6, 2021. Accessed September 19, 2022.

Covid Update: Did Omicron Catch a Cold? 4U Health. Updated December 6, 2021. Accessed September 19, 2022.

Vitamin D & Coronavirus Prevention: Facts & Myths. 4U Health. Updated December 6, 2021. Accessed September 19, 2022.

New Covid-19 Variant Facts: How Did Omicron Start? 4U Health. Updated December 6, 2021. September 19, 2022.

Omicron New Covid-19 Variant Facts: What We Know So Far. 4U Health. Updated December 6, 2021. Accessed September 19, 2022.

At Home Fingerstick Blood Test Facts and Video. 4U Health. Updated December 7, 2021. Accessed September 19, 2022.

Ditch Nose Swabs for a Saliva PCR Covid Test. 4U Health. Updated December 6, 2021. Accessed September 19, 2022.

Can you provide links to references and sources on the Covid antibodies topic?
References and Sources
A.D.A.M. Medical Encyclopedia. COVID-19 antibody test. URL. Updated February 7, 2021. Accessed September 19, 2022.

A.D.A.M. Medical Encyclopedia. COVID-19 virus test. URL. Updated March 15, 2022. Accessed September 19, 2022.

Centers for Disease Control and Prevention. Using antibody tests for COVID-19. URL. Updated February 24, 2022. Accessed September 19, 2022.

Caliendo AM, Hanson KE. COVID-19: Diagnosis. In: Hirsch MS, ed. UpToDate. URL. Updated April 25, 2022. Accessed September 19, 2022.

Centers for Disease Control and Prevention. Test for past infection. URL. Updated August 11, 2022. Accessed September 19, 2022.

Centers for Disease Control and Prevention. COVID-19 testing overview. URL. Updated August 11, 2022. Accessed September 19, 2022.

Centers for Disease Control and Prevention. Interim guidelines for COVID-19 antibody testing. URL. Updated January 24, 2022. Accessed September 19, 2022.

Centers for Disease Control and Prevention. Self Testing. URL. Updated March 9, 2022. Accessed September 19, 2022.

Kim AY, Gandhi RT. COVID-19: Management in hospitalized adults. In: Hirsch MS, ed. UpToDate. URL. Updated August 5, 2022. Accessed September 19, 2022.

McIntosh K. COVID-19: Epidemiology, virology, and prevention. In: Hirsch MS, ed. UpToDate. URL. Updated August 15, 2022. Accessed September 19, 2022.

The New York Times.Wondering if the vaccine worked? Get the right test, at the right time. URL. Updated June 28, 2021. Accessed September 19, 2022.

UpToDate. COVID-19: Questions and answers. URL. Updated August 15, 2022. Accessed September 19, 2022.

UpToDate. Patient education: COVID-19 overview (the basics). URL. Updated August 12, 2022. Accessed September 19, 2022.

US Food and Drug Administration. Antibody (serology) testing for COVID-19: Information for patients and consumers. URL. Updated February 24, 2022. Accessed September 19, 2022.

US Food and Drug Administration. Coronavirus (COVID-19) update: FDA issues emergency use authorization for the symbiotica COVID-19 self-collected antibody test system. URL. Updated April 6, 2021. Accessed September 19, 2022.

US Food and Drug Administration. Coronavirus disease 2019 testing basics. URL. Updated February 28, 2022. Accessed September 19, 2022.

US Food and Drug Administration. In vitro diagnostics EUAs – serology and other adaptive immune response tests for SARS-CoV-2. URL. Updated August 30, 2022. Accessed September 19, 2022.

US Food and Drug Administration. SARS-CoV-2 viral mutations: Impact on COVID-19 tests. URL. Updated August 3, 2021. Accessed September 19, 2022.

World Health Organization.Coronavirus disease (COVID-19): Serology, antibodies and Immunity. URL. Updated December 31, 2020. Accessed September 19, 2022.

Yale Medicine. Which COVID-19 test should you use. URL. Updated January 20, 2022. Accessed September 19, 2022.

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Page Last Updated: October 1, 2022

Page Last Updated: September 24, 2022

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